| Title | Malaria: Drugs, Disease and Post-Genomic Biology |
| Author(s) | D. Sullivan, S. Krishna |
| Publisher | Springer |
| Year | 2005 |
| Edition | 1st Edition |
| Language | English |
| Pages | 452 pages |
| ISBN | 9783540279930 |
| Genre / Domain | Science, Biology, Medicine |
| Series | Unknown |
| Size | 5.49 MB |
| Extension |
Summary
Malaria: Drugs, Disease and Post-Genomic Biology, edited by D. Sullivan and S. Krishna and published by Springer in 2005, is a comprehensive volume that bridges the gap between traditional malariology and the revolutionary advances brought about by the post-genomic era. This book provides a detailed overview of the current state of malaria research, with a particular focus on how genomic, proteomic, and metabolomic technologies are transforming our understanding of the parasite and accelerating the development of new therapeutic strategies.
The book is organized into three main sections, each addressing a critical aspect of malaria research. The first section covers the biology of the malaria parasite, including its life cycle, host-parasite interactions, and the molecular mechanisms underlying drug resistance. The second section focuses on drug discovery and development, reviewing the current arsenal of antimalarial drugs, the challenges of resistance, and the potential of new drug targets identified through genomic approaches. The third section explores the application of post-genomic technologies to malaria research, including genomics, transcriptomics, proteomics, and metabolomics, and how these tools are being used to identify new drug targets and understand the biology of the parasite.
Practical applications of the knowledge presented in this book are significant for researchers and clinicians. The integration of post-genomic approaches has led to the identification of novel drug targets and the development of new screening methods for antimalarial compounds. The book reviews the successes and challenges of these approaches, providing guidance on how to leverage the latest technologies in drug discovery efforts. It also discusses the importance of understanding the parasite's biology at the molecular level to develop more effective and durable therapies.
This book is an essential resource for researchers, graduate students, and professionals in parasitology, tropical medicine, pharmacology, and genomics. It is particularly valuable for those involved in drug discovery and development for malaria and other infectious diseases. The comprehensive coverage of both basic biology and applied research makes it suitable for readers at various stages of their careers, from those new to the field to experienced researchers seeking to update their knowledge.
As a landmark publication, Malaria: Drugs, Disease and Post-Genomic Biology has been praised for its depth, clarity, and relevance to the global fight against malaria. The editors' expertise and the contributions from leading researchers in the field ensure the book's authority and reliability. It remains a key reference for understanding how post-genomic biology is reshaping malaria research and drug discovery.
Key Features
- Provides a comprehensive overview of malaria research in the context of post-genomic biology.
- Edited by leading experts in the field with extensive research experience.
- Covers the biology of the malaria parasite, drug discovery, and post-genomic technologies.
- Reviews the mechanisms of drug resistance and strategies to overcome them.
- Explores the application of genomics, proteomics, and metabolomics to malaria research.
- Discusses the identification of new drug targets and the development of new antimalarial compounds.
- Provides practical guidance for researchers in drug discovery and development.
- Serves as an essential resource for researchers, students, and professionals in parasitology and tropical medicine.
- Includes contributions from leading researchers in the field.
- Published by Springer, a reputable publisher of scientific literature.
- Includes a comprehensive bibliography for further reading.
About the Editors
D. Sullivan is a distinguished researcher in the field of malaria biology and drug discovery. He has made significant contributions to our understanding of the molecular mechanisms of drug resistance in the malaria parasite and the development of new therapeutic strategies. He has published extensively on the subject and is recognized as a leading expert in the field.
S. Krishna is a prominent researcher in the field of infectious diseases, with a particular focus on malaria. He has contributed to the development of new diagnostic tools and therapeutic approaches for malaria and other infectious diseases. He is a respected member of the international research community and has published widely in the field.
Related Books
- Malaria: A Handbook for Health Professionals — Kevin M. De Cock, Wayne L. P. S. E. A. A. M. M. E. A.
- Antimalarial Drug Discovery: From Bench to Bedside — Paul M. O'Neill, John M. Kelly
- Molecular Approaches to Malaria — Irwin W. Sherman
- Reflections on a Century of Malaria Biochemistry — Irwin W. Sherman
- Malaria: Parasite Biology, Pathogenesis, and Protection — Irwin W. Sherman
- Drug Discovery for Infectious Diseases — David A. J. W. M. C. R. A. A. D. E.
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Frequently Asked Questions
Q : What is the main focus of "Malaria: Drugs, Disease and Post-Genomic Biology"?
R : The book explores the intersection of malaria research with post-genomic biology, focusing on the development of new drugs and therapeutic strategies. It covers the latest advances in understanding the malaria parasite's biology, drug resistance mechanisms, and the application of genomic technologies to accelerate drug discovery.
Q : Who are the editors and what are their credentials?
R : The editors are D. Sullivan and S. Krishna, both distinguished researchers in the field of malaria biology and drug discovery. They have extensive experience in molecular parasitology and infectious diseases.
Q : What topics are covered in this book?
R : The book covers the biology of the malaria parasite, drug discovery and development, drug resistance mechanisms, and the application of post-genomic technologies such as genomics, proteomics, and metabolomics to malaria research.
Q : Is this book suitable for students and researchers?
R : Yes, the book is designed for researchers, graduate students, and professionals in parasitology, tropical medicine, pharmacology, and genomics. It provides both a comprehensive overview and detailed insights into the latest advances in the field.
Q : What is the edition and publication year of this book?
R : This is the first edition, published in 2005 by Springer.
Q : How does this book help researchers in drug discovery?
R : The book reviews the application of post-genomic approaches to identify new drug targets and develop new screening methods for antimalarial compounds. It provides guidance on how to leverage these technologies in drug discovery efforts.
Q : Is the book available in digital format?
R : Yes, the book is available in PDF format, making it accessible for digital reading and reference.
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