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The Blood-Brain Barrier and Its Microenvironment: Basic Physiology to Neurological Disease

Book Details
Author Elga de Vries, Alexandre Prat
Publisher CRC Press
Year 2007
Language English
Pages 545
Size 4.40 MB
Extension PDF

Summary

"The Blood-Brain Barrier and Its Microenvironment: Basic Physiology to Neurological Disease" is a seminal work that delves into the intricate mechanisms of the blood-brain barrier (BBB). The BBB is a highly selective semipermeable border that separates the circulating blood from the brain and extracellular fluid in the central nervous system. This book provides a detailed examination of the BBB's structure, function, and its critical role in maintaining brain homeostasis. It also explores how disruptions in the BBB can lead to various neurological diseases, including multiple sclerosis, Alzheimer's disease, and stroke. The authors, Elga de Vries and Alexandre Prat, bring together a wealth of research and clinical insights to offer a comprehensive understanding of the BBB and its microenvironment.

Key Features

  • Comprehensive coverage of the blood-brain barrier's physiology and pathology.
  • In-depth analysis of the BBB's role in neurological diseases.
  • Latest research and advancements in BBB studies.
  • Contributions from leading experts in neuroscience and neurology.
  • Detailed illustrations and diagrams to aid understanding.
  • Practical insights for researchers and clinicians.

About Author

Elga de Vries and Alexandre Prat are renowned researchers and authors in the field of neuroscience. Elga de Vries is a professor at Amsterdam University Medical Centers, specializing in neurovascular biology and the blood-brain barrier. Alexandre Prat is a professor at the University of Montreal, with a focus on neuroimmunology and multiple sclerosis. Together, they have contributed significantly to the understanding of the BBB and its implications in neurological diseases. Their collaborative work in this book reflects their expertise and dedication to advancing the field.

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Frequently Asked Questions

Q: What can I learn by reading this book?

A: This book provides a deep understanding of the blood-brain barrier, its physiological functions, and its role in neurological diseases. Readers will gain insights into the latest research and clinical applications related to the BBB.

Q: Is this book suitable for beginners?

A: While the book is highly detailed and research-oriented, it includes foundational concepts that make it accessible to advanced students and beginners with a strong interest in neuroscience.

Q: Is this book recommended for professionals?

A: Yes, this book is highly recommended for professionals in neuroscience, neurology, and related fields. It offers advanced insights and practical knowledge that are valuable for researchers and clinicians.

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