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The Genetics and Biology of Sex Determination
























The Genetics and Biology of Sex Determination


Author(s):
Novartis Foundation



Collection:
Novartis Foundation symposium 244


Publisher:
Novartis Foundation


Year:
2002


Language:
English


Pages:
275 pages


Size:
2.43 MB


Extension:
PDF





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[content title="Description"]This book reviews and discusses the most recent advances in the understanding of the molecular genetic pathways of sex determination, with special emphasis on vertebrates. Inter alia, coverage includes the genetics and biochemistry of mammalian sex determination, comparisons with other modes of sex determination, and consideration of the biology of sexual development and of the evolution of sex-determining mechanisms. By bringing together an international and interdisciplinary group of experts whose work is focused on many different aspects of the problem, the book reviews much new and exciting work in this area and serves to identify and stimulate promising new research directions.
[/content]

[content title="Content"] [/content]

[content title="About the author"]The Novartis Foundation was a scientific and educational charity, formed in 1949 by the Swiss company Ciba, now Novartis, and dissolved in 2008. It was the direct successor to the Ciba Foundation, and the changed name (Novartis Foundation) reflected the new name of Ciba, after merging with Sandoz.
[/content]

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Biochemistry and Genetics : Pretest Self-Assessment and Review
























Biochemistry and Genetics : Pretest Self-Assessment and Review


Author(s):
Wilson G.N., Schroeder B., Woo J.



Collection:


Publisher:


Year:
2001


Language:
English


Pages:
420 pages


Size:
3.06 MB


Extension:
PDF





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[content title="Description"]These "500 questions, answers, and explanation" books are designed to simulate the United States Medical Licensing Examination (USMLE) Step 1. Each is authored by an expert in the field and has been reviewed by students who have recently passed the exam. As Step 1 is becoming increasingly more clinical in nature, when applicable, clinical vignette-style questions requiring a two-step reasoning process are also included. All of the Pretest titles include a "high-yield" fact section to reinforce key concepts.
[/content]

[content title="Content"] [/content]

[content title="About the author"]Wilson G.N. Schroeder B. are researchers [/content]

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Genetics and human behaviour : the ethical context
























Genetics and human behaviour :  the ethical context


Author(s):
Nuffield Council on Bioethics



Collection:


Publisher:
Nuffield Council on Bioethics


Year:
2002


Language:
English


Pages:
258 pages


Size:
2.51 MB


Extension:
PDF





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[content title="Description"]Genetics and human behaviour: the ethical context--summary and recommendations
Nuffield Council on Bioethics
PMID: 15281207 [/content]

[content title="Content"] [/content]

[content title="About the author"]The Nuffield Council on Bioethics is a UK-based independent charitable body, which examines and reports on bioethical issues raised by new advances in biological and medical research. Established in 1991, the Council is funded by the Nuffield Foundation, the Medical Research Council and the Wellcome Trust.[1] The Council has been described by the media as a 'leading ethics watchdog',[2] which 'never shrinks from the unthinkable'. [/content]

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A Primer of Conservation Genetics
























A Primer of Conservation Genetics


Author(s):
Richard Frankham, Jonathan D. Ballou, David A. Briscoe, Karina H. McInnes



Collection:


Publisher:
Cambridge University Press


Year:
2004


Language:
English


Pages:
236 pages


Size:
3.73 MB


Extension:
PDF





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[content title="Description"]Intended for those with a limited background in genetic studies, this concise, entry-level text in conservation genetics is presented in a user-friendly format, with main points clearly highlighted. Solved problems are provided throughout to help illustrate key equations, although a basic knowledge of Mendelian genetics and simple statistics is assumed. A glossary and suggestions for further reading provide additional support for the reader. Numerous pen-and-ink portraits of endangered species bring the material to life. Also available: Introduction to Conservation Genetics "...balance[s] student need for clarity and brevity with the requirements of conservation professionals for detailed applications." Choice 0-521-63014-2 Hardback $130.00 C 0-521-63985-9 Paperback $50.00 D [/content]

[content title="Content"] [/content]

[content title="About the author"]Richard Frankham, Australian conservation geneticist, educator. Member Genetics Society Australia (honorary treasurer auditor 1973-1975), Society for Conservation Biology (organizing committee 12th meeting 1996-1998). [/content]

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Introduction to generalized functions with applications in aeroacoustics
























 Introduction to generalized functions with applications in aeroacoustics


Author(s):
Farassat F.



Collection:


Publisher:
NASA


Year:
1994


Language:
English


Pages:
53 pages


Size:
359 KB


Extension:
DJVU





[tab]

[content title="Description"]Generalized functions have many applications in science and engineering. One useful aspect is that discontinuous functions can be handled as easily as continuous or differentiable functions and provide a powerful tool in formulating and solving many problems of aerodynamics and acoustics. Furthermore, generalized function theory elucidates and unifies many ad hoc mathematical approaches used by engineers and scientists. We define generalized functions as continuous linear functionals on the space of infinitely differentiable functions with compact support, then introduce the concept of generalized differentiation. Generalized differentiation is the most important concept in generalized function theory and the applications we present utilize mainly this concept. First, some results of classical analysis, are derived with the generalized function theory. Other applications of the generalized function theory in aerodynamics discussed here are the derivations [/content]

[content title="Content"] [/content]

[content title="About the author"] Fereidoun Farassat was born on October 20, 1944. Fereidoun died on July 9, 2011 at 66 years of age. We know that Fereidoun Farassat had been residing in Hampton, Hampton City County, Virginia 23669. [/content]

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Evolutionary Conservation Genetics
























Evolutionary Conservation Genetics


Author(s):
Jacob Höglund



Collection:


Publisher:
Oxford University Press, USA


Year:
2009


Language:
English


Pages:
208 pages


Size:
3.46 MB


Extension:
PDF





[tab]

[content title="Description"]Conservation genetics focuses on understanding the role and requirement of genetic variation for population persistence. However, considerable debate now surrounds the role of genetic factors (as opposed to non-genetic factors such as habitat destruction etc.) in population extinction, and a comprehensive synthesis is now timely. Can extinction be explained by habitat destruction alone or is lack of genetic variation a part of the explanation? The book thoroughly reviews the arguments for a role of genetics in the present biodiversity crisis. It describes the methods used to study genetic variation in endangered species and examines the influence of genetic variation in the extinction of species. To date, conservation genetics has predominantly utilized neutral genetic markers e.g. microsatellites. However, with the recent advances in molecular genetics and genomics it will soon be possible to study 'direct gene action', following the fate of genetic variation at the level of DNA, through expression, to proteins in order to determine how such phenotypes fare in populations of free living organisms. Evolutionary Conservation Genetics explores these exciting avenues of future research potential, integrating ecological quantitative genetics with the new genome science. It is now more important than ever that we ask relevant questions about the evolutionary fate of endangered populations throughout the globe and incorporate our knowledge of evolutionary processes and the distribution of genetic diversity into effective conservation planning and action. [/content]

[content title="Content"] [/content]

[content title="About the author"]Professor of Animal Conservation Biology. Me and my research group are interested in the importance of genetic variation for the persistance of small and ... [/content]

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Introduction To Molecular Genetics And Geonomics
























Introduction To Molecular Genetics And Geonomics


Author(s):
Hearts



Collection:


Publisher:


Year:


Language:
English


Pages:
132 pages


Size:
4.24 MB


Extension:
PDF





[tab]

[content title="Description"]Molecular Genetics and Genomics (MGG) publishes peer-reviewed articles covering all areas of genetics and genomics. Any approach to the study of genes and genomes is considered, be it experimental, theoretical or synthetic. MGG publishes research on all organisms that is of broad interest to those working in the fields of genetics, genomics, biology, medicine and biotechnology [/content]

[content title="Content"] [/content]

[content title="About the author"]Heart is an American rock band formed in 1967 in Seattle, Washington, as The Army. Two years later they changed their name to Hocus Pocus. The year following they changed their name to White Heart, and eventually changed the name a final time to Heart, in 1973 [/content]

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Nature's Clocks. How Scientists Measure the Age of Almost Everything
























Nature's Clocks. How Scientists Measure the Age of Almost Everything


Author(s):
Doug Macdougall



Collection:


Publisher:
University of California Press


Year:
2009


Language:
English


Pages:
285 pages


Size:
1.81 MB


Extension:
PDF





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[content title="Description"]"Radioactivity is like a clock that never needs adjusting," writes Doug Macdougall. "It would be hard to design a more reliable timekeeper." In Nature's Clocks, Macdougall tells how scientists who were seeking to understand the past arrived at the ingenious techniques they now use to determine the age of objects and organisms. By examining radiocarbon (C-14) dating--the best known of these methods--and several other techniques that geologists use to decode the distant past, Macdougall unwraps the last century's advances, explaining how they reveal the age of our fossil ancestors such as "Lucy," the timing of the dinosaurs' extinction, and the precise ages of tiny mineral grains that date from the beginning of the earth's history. In lively and accessible prose, he describes how the science of geochronology has developed and flourished. Relating these advances through the stories of the scientists themselves--James Hutton, William Smith, Arthur Holmes, Ernest Rutherford, Willard Libby, and Clair Patterson--Macdougall shows how they used ingenuity and inspiration to construct one of modern science's most significant accomplishments: a timescale for the earth's evolution and human prehistory. [/content]

[content title="Content"] [/content]

[content title="About the author"]Doug Macdougall is an author, geoscientist, and educator. He currently lives in Edinburgh, Scotland, with his wife Sheila.

As is true for many people, my career has been charted partly through serendipity. Growing up in Ontario, Canada, I was especially interested in nature and the outdoors. By the time I was in high school I was convinced that I wanted to be an ornithologist – a friend had introduced me to the panorama of bird life that annually flows through southern Ontario. But at the University of Toronto a first year course in geology, with slides from exotic locales around the world, coupled with the sometimes unpleasant dissections we had to perform in a biology class (we were required to cut up everything from earthworms to frogs and fetal pigs), turned my focus to the earth sciences. [/content]

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Phylogenetics : the theory and practice of phylogenetic systematics
























Phylogenetics : the theory and practice of phylogenetic systematics


Author(s):
E. O. Wiley



Collection:


Publisher:
Wiley-Liss


Year:
1981


Language:
English


Pages:
452 pages


Size:
4.47 MB


Extension:
DJVU





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[content title="Description"]Presents a clear, simple and comprehensive overview of the phylogenetic approach to systematics, which has two major goals: reconstructing the evolutionary relationships among organisms and integrating the results into general reference classifications. Shows how the results of systematic research can be applied to studying the pattern and processes of evolution.
[/content]

[content title="Content"] [/content]

[content title="About the author"]E. O. Wiley (1944 - ) was born Edward Orlando Wiley, III, in Corpus Christi, Texas. He grew up in mostly in San Marcos, Texas where he graduated from Southwest Texas State College (now Texas State University with a degree in biology, minor in chemistry. After one year as a fisheries biologist for the Texas Parks and Wildlife he joined the U.S. Air Force. After four years with assignments in Kansas, Key West, Florida and Alaska he returned to school at Sam Houston State University (M.A) and City University of New York (Ph.D.). During his tenure at the University of Kansas he has specialized in the theory and practice of systematic biology and studied the evolution of fishes as a member of the Department of Ecology and Evolutionary Biology and Senior Curator of Fishes at the Biodiversity Institute. Honors include election as a Fellow to the Linnean Society, London, President of the Society of Systematic Zoology (now Biology) and a recipient of the Gibbs Award for an outstanding body of work in the [/content]

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Multifactor explanations of asset pricing anomalies
























Multifactor explanations of asset pricing anomalies


Author(s):
Fama E.F., French K.R.



Collection:


Publisher:


Year:
1996


Language:
English


Pages:
31 pages


Size:
3.20 MB


Extension:
PDF





[tab]

[content title="Description"]Previous work shows that average returns on common stocks are related to firm characteristics like size, earnings/price, cash flow/price, book-to-market equity, past sales growth, long-term past return, and short-term past return. Because these patterns in average returns apparently are not explained by the CAPM, they are called anomalies. We find that, except for the continuation of short-term returns, the anomalies largely disappear in a three-factor model. Our results are consistent with rational ICAPM or APT asset pricing, but we also consider irrational pricing and data problems as possible explanations.
[/content]

[content title="Content"] [/content]

[content title="About the author"]Eugene F. Fama, 2013 Nobel laureate in economic sciences, is widely recognized as the "father of modern finance." His research is well known in both the academic and investment communities. He is strongly identified with research on markets, particularly the efficient markets hypothesis. He focuses much of his research on the relation between risk and expected return and its implications for portfolio management. His work has transformed the way finance is viewed and conducted. [/content]

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Theoretical Evolutionary Genetics
























Theoretical Evolutionary Genetics


Author(s):
Felsenstein J.



Collection:


Publisher:


Year:
2003


Language:
English


Pages:
383 pages


Size:
2.47 MB


Extension:
PDF





[tab]

[content title="Description"]This is a text which is used in my Genome 562 course. It was originally written in the late 1970's, and many parts of it have not been updated since about 1981. A major part of the new chapter on molecular population genetics and most of a chapter on multiple linked loci, plus a chapter on polygenic characters in natural populations, has been added more recently. It was to be a book, but I became involved in work on phylogenies, and it has been published as lecture notes ever since. A small amount of new material has been added each time it was privately reprinted by me for use in my class. It was originally on a magnetic-card storage system for electric typewriters, and then migrated to the Runoff family of mathematical text formatting systems, and finally to LaTeX with Postscript figures.
[/content]

[content title="Content"] [/content]

[content title="About the author"]Joseph "Joe" Felsenstein (born May 9, 1942[2]) is a Professor Emeritus in the Departments of Genome Sciences and Biology at the University of Washington in Seattle. He is best known for his work on phylogenetic inference, and is the author of Inferring Phylogenies, and principal author and distributor of the package of phylogenetic inference programs called PHYLIP. Closely related to his work on phylogenetic inference is his introduction of methods for making statistically independent comparisons using phylogenies. [/content]

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The Surface Chemistry of Natural Particles
























The Surface Chemistry of Natural Particles


Author(s):
Garrison Sposito



Collection:


Publisher:
Oxford University Press, USA


Year:
2004


Language:
English


Pages:
253 pages


Size:
2.12 MB


Extension:
PDF





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[content title="Description"]This book recounts the development of experiment and theory in natural particle surface chemistry over the past 20 years. It offers a broadly based discussion of molecular spectroscopy, kinetics, and equilibria as they apply to natural particle surface reactions in aqueous media, with emphasis on insights gained over the past few years. After a review of qualitative notions about ion adsorption by natural particles, the strategies and theory of four spectroscopic approaches to studying natural particles are described, current models of surface chemical kinetics and equilibria are examined, and natural particle colloidal phenomena are detailed. Discussion is accompanied by lengthy annotations and reading suggestions, and punctuated by end-of-chapter problem sets that require a critical reading of important technical journal articles.
[/content]

[content title="Content"] [/content]

[content title="About the author"]Professor Sposito has been elected a Fellow of six international scientific societies and has been a Fulbright Lecturer (Theoretical Physics) as well as a Guggenheim Fellow (Applied Mathematics). He received the Soil Science Research Award from the Soil Science Society of America, and in 2008 was designated a “Legend in Environmental Chemistry” by the American Chemical Society, the world’s largest scientific organization. He is the recipient of three hydrologic science honors bestowed by the American Geophysical Union, the world's largest earth science organization, including its Robert E. Horton Medal, for "outstanding contributions to the geophysical aspects of hydrology;" the Hydrologic Sciences Award of its Hydrology Section, for "outstanding contributions to the science of hydrology;" and the Walter B. Langbein Lectureship, "awarded for contributions to the basic science of hydrology." A Phi Beta Kappa Teaching Excellence laureate, he is also the only person to receive campus-wide Distinguished Teaching Awards from both state university systems in California. [/content]

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Factorial and time course designs for cDNA microarray experiments
























Factorial and time course designs for cDNA microarray experiments


Author(s):
Glonek G.F., Solomon P.J.



Collection:


Publisher:


Year:
2004


Language:
English


Pages:
23 pages


Size:
1.73 MB


Extension:
PDF





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[content title="Description"]Microarrays are powerful tools for surveying the expression levels of many thousands of genes simultaneously. They belong to the new genomics technologies which have important applications in the biological, agricultural and pharmaceutical sciences. There are myriad sources of uncertainty in microarray experiments, and rigorous experimental design is essential for fully realizing the potential of these valuable resources. Two questions frequently asked by biologists on the brink of conducting cDNA or two-colour, spotted microarray experiments are 'Which mRNA samples should be competitively hybridized together on the same slide?' and 'How many times should each slide be replicated?' Early experience has shown that whilst the field of classical experimental design has much to offer this emerging multi-disciplinary area, new approaches which accommodate features specific to the microarray context are needed. In this paper, we propose optimal designs for factorial and time course experiments, which are special designs arising quite frequently in microarray experimentation. [/content]

[content title="Content"] [/content]

[content title="About the author"]Peter J. Solomon (born September 17, 1938) is an American investment banker and the founder and chairman of Solomon Partners, one of the country's first independent investment banks. He is also a former New York City Deputy Mayor for Economic Policy and Development. [/content]

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The biology of genetic dominance
























The biology of genetic dominance


Author(s):
Reiner A. Veitia



Collection:
Molecular biology intelligence unit


Publisher:
Landes Bioscience _, Eurekah.com


Year:
2006


Language:
English


Pages:
167 pages


Size:
3.97 MB


Extension:
PDF





[tab]

[content title="Description"]Biologists, physicists, and other researchers explore the bases of Mendelian dominance as a pre-requisite for understanding the more complex non-Mendelian inheritance. Their topics include the phenomenology and mechanisms of dominance, phenotype and stochastic gene expression, mathematical models of haplo-insufficiency, biological consequences of dosage-dependent gene regulation in multicellular eukaryotes, and lessons from a genetic network about the causes of dominance. [/content]

[content title="Content"] [/content]

[content title="About the author"]Reiner Veitia. Paris, Ile-de-France, France. Specialties : Biochemistry And Molecular Genetics, Cell And Developmental Biology. [/content]

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Genetic Systems Programming : Theory and Experiences
























Genetic Systems Programming : Theory and Experiences


Author(s):
Ajith Abraham



Collection:
Studies in Computational Intelligence


Publisher:
Springer


Year:
2009


Language:
English


Pages:
247 pages


Size:
3.94 MB


Extension:
PDF





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[content title="Description"]Designing complex programs such as operating systems, compilers, filing systems, data base systems, etc. is an old ever lasting research area. Genetic programming is a relatively new promising and growing research area. Among other uses, it provides efficient tools to deal with hard problems by evolving creative and competitive solutions. Systems Programming is generally strewn with such hard problems. This book is devoted to reporting innovative and significant progress about the contribution of genetic programming in systems programming. The contributions of this book clearly demonstrate that genetic programming is very effective in solving hard and yet-open problems in systems programming. Followed by an introductory chapter, in the remaining contributed chapters, the reader can easily learn about systems where genetic programming can be applied successfully. These include but are not limited to, information security systems, compilers, data mining systems, stock market prediction systems, robots and automatic programming. [/content]

[content title="Content"] [/content]

[content title="About the author"]Dr. Ajith Abraham received Ph.D. degree from Monash University, Melbourne Australia and a Master of Science Degree from Nanyang technological University, Singapore. His research and development experience includes over 17 years in the Industry and Academia spanning different continents in Australia, America, Asia and Europe. He works in a multi-disciplinary environment involving computational intelligence, network security, sensor networks, e-commerce, Web intelligence, Web services, computational grids, data mining and applied to various real world problems. He has authored/co-authored over 350 refereed journal/conference papers and book chapters and some of the papers have also won best paper awards at international conferences and also received several citations. Some of the articles are available in .. [/content]

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Genetic Techniques for Biological Research : A Case Study Approach
























Genetic Techniques for Biological Research : A Case Study Approach


Author(s):
Corinne A. Michels



Collection:


Publisher:
Wiley


Year:
2002


Language:
English


Pages:
237 pages


Size:
2.65 MB


Extension:
DJVU





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[content title="Description"]Molecular Genetic Analysis is an advanced textbook to teach the theory and practice of molecular genetic analysis to senior undergraduates and graduates studying genetics, molecular biology and cell biology.
This book uses a case study approach, with the yeast Saccharomyces as the model genetic organism, to explain the theory and practice of molecular genetic analysis. It provides enough information so readers will be able to apply the approach to their own research project. [/content]

[content title="Content"] [/content]

[content title="About the author"]Dr. Michels' professional career is dedicated to genetics - its teaching and use as a research tool to study all areas of biology and medicine. She first became interested in genetics as a college student majoring in biology. The Nobel Prize had recently been awarded to James Watson, Francis Crick, and Maurice Wilkins (1962) for revealing the structure of DNA and proposing how this molecule, known since 1943 to be the hereditary material, could duplicate and encode information for the formation of a living organism. After taking a course in biochemical genetics and learning about the work of other Nobel laureates who studied genetics, like Thomas Hunt Morgan (1933) of white eyed fruit fly fame; George Beadle and Edward Tatum (1958), the originators of the “one gene – one enzyme” hypothesis; and Joshua Lederberg (1958), who mapped the E. coli chromosome, Dr. Michels was hooked. She decided to train to be a geneticist with the goal of understanding the molecular basis of heredity, embryological development, disease, and human evolution. But it was only after the completion of her college senior thesis, on what was to be the Nobel Prize winning work of François Jacob, André Lwoff, and Jacques Monod (1965) on the genetic control of enzyme synthesis and virus replication, that she focused specifically on the regulation of gene expression. Dr. Michels' interest in genetics and the genetic approach to problem solving has been sustained throughout her career.
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DNA Topoisomerase Protocols - Volume 2
























DNA Topoisomerase Protocols - Volume 2


Author(s):
Osheroff N., Bjornsti M.A.



Collection:
Methods in Molecular Biology 095


Publisher:


Year:
2000


Language:
English


Pages:
329 pages


Size:
4.00 MB


Extension:
PDF





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[content title="Description"]An unprecedented collection of cutting-edge experimental protocols for investigating the catalytic activities of DNA topoisomerases, as well as their specific interactions with topoisomerase-targeted antitumor and antibacterial drugs. Described by expert experimentalists who have perfected the techniques, these unfailingly reproducible methods include assays for enzyme-catalyzed DNA relaxation/supercoiling, DNA cleavage, DNA nicking, DNA decatenation, and ATP hydrolysis. Several modified DNA substrates, used to dissect enzyme mechanisms by trapping intermediates, are also described. Methodologies to determine the action of topoisomerase-targeted drugs include biochemical assays of drug-induced enzyme-DNA complexes, methods for assaying drug uptake, and cell-based assays for determining the specificity and mechanisms of drug resistance. A companion volume, DNA Topoisomerase Protocols, I: DNA Topology and Enzymes, provides state-of-the-art experimental protocols for investigating DNA structure, topology, and DNA topoisomerase function.
[/content]

[content title="Content"] [/content]

[content title="About the author"]Neil Osheroff, Ph.D.
Professor of Biochemistry
Professor of Medicine (Hematology/Oncology)
John G. Coniglio Chair in Biochemistry
Past-Director, Academy for Excellence in Education
Co-Leader, Foundations of Medical Knowledge Phase.Mary-Ann Bjornsti, Ph.D., is Chair of the Department of Pharmacology and Toxicology at UAB, and holds the Newman H. Waters Chair of Clinical Pharmacology. She also serves as co-Leader of the Cancer Cell Biology Program and Associate Director for Translational Research in the UAB Comprehensive Cancer Center. She received her Ph.D. from the University of Minnesota in Genetics, followed by a Fogarty Fellowship at the Biozentrum in Basel Switzerland, and post-doctoral training at Harvard University with Dr. James C. Wang. [/content]

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Genomic Imprinting : Methods and Protocols
























Genomic Imprinting : Methods and Protocols


Author(s):
Wendy L. Dean, Gavin Kelsey, Wolf Reik , Andrew Ward



Collection:
Methods in Molecular Biology 181


Publisher:
Humana Press


Year:
2002


Language:
English


Pages:
389 pages


Size:
1.95 MB


Extension:
PDF





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[content title="Description"]Imprinted genes, many of which generally control growth and development, frequently lose their imprints during cancer progression, a loss that then plays a substantial role in uncontrolled tumor growth. Imprint instability also appears to be a major limitation to the success of mammalian cloning experiments. In Genomic Imprinting: Methods and Protocols, Andrew Ward and a team of experienced researchers have brought together a collection of optimized classic and vanguard techniques for the identification and analysis of imprinted genes. The majority of protocols describe molecular techniques that allow examination of gene structure or expression in an allele-specific manner. Protocols are included for identifying and cloning imprinted genes, for analyzing imprinted gene expression, for the study of DNA methylation and methylation-sensitive DNA-binding proteins, and for examining chromatin structure. There are also methods for the manipulation of mouse embryos to produce monoparental embryos and embryonic stem cells, and for the generation of transgenic mice with BAC, PAC, and YAC constructs. Each technique is described in step-by-step detail to ensure successful results.
Incorporating a wealth of knowledge from leading exponents in the field, Genomic Imprinting: Methods and Protocols brings together all the essential molecular, genetic, and embryological methods commonly used in today's laboratories for the identification and analysis of imprinted genes. [/content]

[content title="Content"] [/content]

[content title="About the author"]Wendy Dean, MD is a psychiatrist, who also practiced as an emergency room physician, trained as a surgeon, worked for the U.S. Army, and been an executive at a large international non-profit. Her own personal experiences as a physician, a family member, and a patient, inform her unflinching advocacy for clinicians and patients alike.

Dean is the CEO and co-founder, with Simon G. Talbot, MD, of The Moral Injury of Healthcare (fixmoralinjury.org), a nonprofit organization reframing how best to understand and address distress in the healthcare workforce. Together they also cohost the podcast, Moral Matters.Gavin obtained a B.Sc. in Biochemistry from King’s College London and then a Ph.D. in Genetics from University College London. Between 1987 and 1995 he was a post-doc at the German Cancer Research Center in Heidelberg, where he held a long-term post-doctoral fellowship from EMBO (1987-1999). In 1995 Gavin joined the Babraham Institute as a Group Leader, holding an MRC senior (non-clinical) fellowship from 1995-2005. He came to Babraham to identify and characterise new imprinted genes. [/content]

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Mobile Genetic Elements: Protocols and Genomic Applications
























Mobile Genetic Elements:  Protocols and Genomic Applications


Author(s):
Wolfgang J. Miller, Pierre Capy



Collection:
Methods in Molecular Biology 260


Publisher:
Humana Press


Year:
2004


Language:
English


Pages:
292 pages


Size:
3.75 MB


Extension:
PDF





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[content title="Description"]Transposable elements (TEs)-DNA sequences that are capable of moving from one chromosome location to another-are found in all living organisms. They have been increasingly investigated in a wide spectrum of species, including bacteria, plants, fungi, and animals. In Mobile Genetic Elements: Protocols and Genomic Applications, leading experts describe in step-by-step detail their most productive transposon-based methods and strategies for studying genome structure, function, and evolution. These readily reproducible techniques cover a broad range, including mutagenesis, transgenesis, gene silencing, and molecular systematics. Among the highlights are a series of DNA hybridization methods for analyzing the distribution and dynamics of mobile DNA at the hosts' genomic level, techniques for studying LTR retrotransposons in heterologous host systems, and mutagenesis protocols for investigating gene functions in a broad range of organisms. Additional methods deal with highly informative sets of polymorphic markers, RNAi technology in gene silencing, and applications during transgenesis. The protocols presented follow the successful Methods in Molecular Biology™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
[/content]

[content title="Content"] [/content]

[content title="About the author"]Wolfgang Miller
Center of Anatomy and Cell Biology, Medical University of Vienna
Bestätigte E-Mail-Adresse bei meduniwien.ac.at [/content]

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Psychiatric Genetics. Methods and Reviews
























Psychiatric Genetics. Methods and Reviews


Author(s):
Marion Leboyer, Frank Bellivier



Collection:
Methods in Molecular Biology


Publisher:
Humana Press


Year:
2002


Language:
English


Pages:
259 pages


Size:
1.24 MB


Extension:
PDF





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[content title="Description"]Psychiatric Genetics provides the reader with a complete view of the methodological problems encountered in psychiatry genetics and proposes solutions to commonly occurring questions. The best European and American specialists have given a thorough review on the advantages and disadvantages of genetic epidemiological methods, the way to choose a genetic marker or a clinical interview and how to ascertain patients, unaffected relatives and controls and what should be the criteria to include a case or a control. New phenotypic methods are described focusing on candidate symptom and endophenotype approaches. Examples coming from cognitive neurosciences, biochemistry, electrophysiology and brain imaging techniques are reviewed. This book will serve as an essential handbook for psychiatrists, psychologists, and geneticists involved in the genetics of psychiatric disorders. [/content]

[content title="Content"] [/content]

[content title="About the author"]After studying medicine at Paris Descartes University , a master's degree and a science thesis at Pierre and Marie Curie University , and having been appointed intern at the Paris hospitals in 1981, she was head of clinic at the hospital . de La Pitié-Salpêtrière from 1989 to 1994. From 2002 to 2007, she was head of the sectorized psychiatry service of the Albert Chenevier hospital and of the psychiatry service of the Henri Mondor hospital in 2002 before being appointed head of the psychiatry center 2 . Since 2019, she has been medical director of the Innovation in Mental Health, Psychiatry and AddiCTology university hospital department of Grand-Paris-Sud(DMU IMPACT) 3 within the Henri-Mondor University Hospital Center ( AP-HP ) and the University Hospital Federation of Precision Medicine in Psychiatry and Addiction (FHU ADAPT) since 2020 [/content]

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